Signaling between cells in physical contact.

A signaling molecule (ligand) binds to a specific receptor on the cell surface or inside the cell.

The receptor triggers a relay of intracellular molecules, often called a signaling cascade (e.g., using G-proteins or kinases).

Long-distance signaling via the bloodstream (e.g., hormones).

Common transducers include G-protein coupled receptors (GPCRs) , which use secondary messengers like cyclic AMP (cAMP) to amplify signals. 2. Signaling Theory (Economics & Management) Signaling Theory: A Review and Assessment - Sage Journals

The signal finally triggers a specific cellular activity, such as gene expression or enzyme activation. Types of Signaling: Autocrine: A cell targets itself.