Reckless — [s8e10]

Software for motif discovery and next generation sequencing analysis

HOMER (Hypergeometric Optimization of Motif EnRichment) is a suite of tools for Motif Discovery and ChIP-Seq analysis. It is a collection of command line programs for unix-style operating systems written in mostly perl and c++. Homer was primarily written as a de novo motif discovery algorithm that is well suited for finding 8-12 bp motifs in large scale genomics data.

Hardware Requirements (recommended): 2+ Gb memory (4-8+ Gb), 10+ Gb Hard Drive space (50+ Gb)
Software Requirements: Unix compatible OS (or cygwin), perl, gcc, make, wget (optional for full functionality: R, DESeq2, blat, bedGraphToBigWig, liftOver)
License: GPLv3

HOMER works on pretty much any Linux/UNIX systems, including MacOS (if Xcode compilers are installed) and on Windows using either cygwin or a Linux subsystem.

If you are looking specifically for HOMER2, you are in the right place! HOMER2 is integrated into HOMER.

Full Program Download

Reckless — [s8e10]

: Frost recklessly volunteers herself as bait, despite Barry Allen’s strong objections and fear for her safety. She collaborates with her mother, Dr. Carla Tannhauser, to amplify her powers. The experiment nearly turns fatal when Carla suffers a medical emergency while trying to help.

In , titled " Reckless ," the central theme revolves around the dangerous choices made by Team Flash as they struggle to contain a mysterious new threat. Plot Overview [S8E10] Reckless

: Barry finds his leadership tested as he reluctantly agrees to Frost’s risky plan, struggling with the dilemma of the "greater good" versus protecting his immediate family. : Frost recklessly volunteers herself as bait, despite

: In Coast City, Iris West-Allen’s "time sickness" worsens. Accompanied by Sue Dearbon, she attempts to help a teenager named Tinya Wazzo find her birth mother. However, Iris’s unstable condition leads to a tragic accident where she unintentionally causes Tinya’s mother to vanish. Key Character Moments The experiment nearly turns fatal when Carla suffers

: Team Flash continues their search for the "Black Flame," a mysterious entity causing cold fusion deaths across Central City. To trap it, Chester Runk proposes using a Cold Fusion Reactor, but the plan requires a powerful cryo-signature to act as bait.

: Tinya Wazzo, known to DC fans as Phantom Girl, is formally introduced as she searches for her roots. REVIEW: The Flash – Season 8, Episode 10 "Reckless"

Program Components and Older Versions

homer2 program - key executable for HOMER motif discovery (homerCppOnly.*.zip). (This archive actually contains all of the c++ executable, not just homer2). Unzip in the desired directory and simply type "make" to compile the program.

The configuration script really doesn't deal with older versions, but you can download older versions yourself should you really feel like using inferior data or software!

Old Versions of HOMER Software
Old Versions of Organism Packages
Old Versions of Promoter Packages
Old Versions of Genome Packages

Update Information

Change Log - Short description of recent changes

update.txt - Current HOMER configuration list (Currently support human hg17/hg18/hg19, mouse mm8/mm9, rat rn4, X. tropicalis xenTro2, drosophila dm3, and C. elegans ce6, Zebrafish danRer7, yeast sacCer2, Arabidopsis tair10, Rice msu6, Pombe ASM294v1)

Can't figure something out? Questions, comments, concerns, or other feedback:
cbenner@ucsd.edu