If you are specifically looking at the 5.x series, it introduced several major usability and quality upgrades over previous versions:
: Version 5 produces "cleaner and crispier" results by using improved spatial and temporal filters that better distinguish between fine detail and noise. neat-video-pro-5-4-1-plugins-full-version
The plugin is widely used across major editing platforms. You can find more details or download trial versions on the official Neat Video website. and After Effects DaVinci Resolve Final Cut Pro Magix Video Pro and Edius If you are specifically looking at the 5
: Unlike the Home version, which is restricted to 1920x1080 (HD), the Pro version supports unlimited frame sizes , making it essential for 4K, 8K, and larger resolution projects. and After Effects DaVinci Resolve Final Cut Pro
: It includes a high-precision processing mode specifically designed for VFX, CGI, and demanding film restoration tasks. Core Functionality Improvements in Version 5