Mitochondria And Longevity Review
Unlike nuclear DNA, mitochondrial DNA (mtDNA) lacks robust repair mechanisms and sits right next to the "exhaust" of energy production, making it highly susceptible to mutations.
As we age, several factors compromise our cellular energy production: Mitochondria and longevity
Mitochondria generate 90% of the body's energy through a process called oxidative phosphorylation. However, this "dirty" process creates reactive oxygen species (ROS) as a byproduct. While low levels of ROS can act as beneficial signaling molecules (a concept called ), chronic accumulation causes oxidative stress that damages DNA and proteins, accelerating the aging clock. Why Mitochondrial Health Declines Unlike nuclear DNA, mitochondrial DNA (mtDNA) lacks robust
Compounds like CoQ10 , PQQ , and Alpha-Lipoic Acid support the electron transport chain. While low levels of ROS can act as
Certain dietary habits and nutrients act as "cellular fuel" or "cleanup crews":
Melatonin is more than a sleep hormone; it is produced within the mitochondria themselves and acts as a powerful antioxidant to protect them from overnight damage. The Future of Anti-Aging