Primarily clinical, identified by pain at the radial styloid (base of the thumb). The Finkelstein maneuver —where the thumb is tucked into a fist and the wrist is bent toward the pinky—is the standard provocative test. Treatment Review

Most common in women (especially aged 30–50) and frequently associated with postpartum care (lifting infants). Other triggers include repetitive thumb activities like texting, gaming, golfing, or racquet sports.

De Quervain's tenosynovitis (DQT) is a painful, stenosing condition of the first dorsal compartment of the wrist, where the and extensor pollicis brevis (EPB) tendons reside . It is primarily characterized by thickening and swelling of the extensor retinaculum, which causes increased friction and restricts the smooth gliding of these tendons. Key Characteristics & Etiology

While often called "inflammation," modern research suggests it may be a degenerative process (tendinosis) rather than a purely inflammatory one.

Most patients respond well to non-operative management, which is typically considered the first line of defense. Management of de Quervain Tenosynovitis - JAMA Network